Figure 3
From: LIM only 4 is overexpressed in late stage pancreas cancer
LMO4 expressions in pancreatic cancer cell lines, a human pancreatic ductal epithelial (HPDE) cell line and primary fibroblasts derived from pancreatic tumors. Hs766T, AsPC-1, SUIT-2, CAPAN-1, KP-3, KP-2, CAPAN-2, PANC-1 and MIA PaCa-2 cells expressed significantly higher levels of LMO4 (median, 1.07) than did the HPDE cells (median, 0.46). All 6 cultures of primary fibroblasts express moderate levels of LMO4 (median, 0.70). The difference in LMO4 expression between the metastasis group (Hs766T, AsPC-1, SW1990, NOR-P1, SUIT-2 and CAPAN-1; median = 1.06) and the non-metastasis group (KP-2, KP-3, CAPAN-2, PANC-1, MIA PaCa-2 and H48N; median = 0.76) is not statistically significant (p = 0.75). Expression of LMO4 mRNA was normalized to that of 18S rRNA.