Table 2 Cox regression analysis.
From: Expression of the neuron-specific protein CHD5 is an independent marker of outcome in neuroblastoma
Overall Survival | ||||||
|---|---|---|---|---|---|---|
Variable | HR and 95%CI | p-value | Variable | HR and 95%CI | p-value | Interaction p-value& |
CHD5 IHC | 21.28 (2.84-159.39) | 0.003 | ||||
CHD5 IHC | 18.67 (2.27-153.88) | 0.007 | 0.951 | |||
INSS | 4.15 (1.63-10.58) | 0.003 | INSS | 1.24 (0.46-3.29) | 0.673 | |
CHD5 IHC | 15.17 (1.89-121.73) | 0.011 | 0.931 | |||
Age (>12 m) | 5.56 (1.61-19.19) | 0.007 | Age (>12 m) | 2.14 (0.59-7.75) | 0.249 | |
CHD5 IHC | 12.29 (1.56-96.49) | 0.017 | 0.952 | |||
MYCN (*) | 14.27 (4.28-47.58) | < 0.001 | MYCN (*) | 8.08 (2.43-26.93) | 0.001 | |
CHD5 IHC | 14.33 (1.84-111.48) | 0.011 | 0.946 | |||
LOH(**) | 2.88 (1.04-7.96) | 0.042 | LOH(**) | 1.75 (0.63-4.89) | 0.287 | |
Event Free Survival | ||||||
Variable | HR and 95%CI | p-value | Variable | HR and 95%CI | p-value | Interaction p-value & |
CHD5 IHC | 8.14 (2.82-23.5) | <0.001 | ||||
CHD5 IHC | 7.01 (2.09 to 23.51) | 0.002 | 0.939 | |||
INSS | 3.7 (1.73-7.88) | 0.001 | INSS | 1.26 (0.53 to 2.97) | 0.605 | |
CHD5 IHC | 7.04 (2.24 to 22.09) | 0.001 | 0.638 | |||
Age (>12 m) | 3.13 (1.33-7.39) | 0.009 | Age (>12 m) | 1.36 (0.54 to 3.44) | 0.515 | |
CHD5 IHC | 5.97 (1.98 to 17.98) | 0.001 | 0.933 | |||
MYCN (*) | 4.58 (1.84-11.42) | 0.001 | MYCN | 2.72 (1.07 to 6.88) | 0.035 | |
CHD5 IHC | 6.02 (1.98 to 18.34) | 0.002 | 0.492 | |||
LOH(**) | 2.12 (0.92-4.91) | 0.079 | LOH | 1.24 (0.52 to 2.95) | 0.622 |