PTEN suppresses cell death and tumor emergence caused by RB/p107 loss in the retina. All mice are positive for CHX10-cre. A. H&E stained sections (representative of n = 3) from 8-month-old mice (except TKO; 5 month old) of the stated genotypes, Scale bar, 20 μm. B. Kaplan-Meier analysis for the % non-moribund status of the indicated mice. P values were determined by log rank test comparing a genotype with that of the control mice. C. H&E-stained sections from mouse eyes of the stated genotypes at 3, 7, 15, 30 and 90 days of age. Scale bar, 200 μm. See also Additional file 1: Figure S1.