Table 2 Univariate survival analysis of 168 patients with HCC
From: Over-expression of cathepsin B in hepatocellular carcinomas predicts poor prognosis of HCC patients
Variable | n | Overall survival | P value | |
|---|---|---|---|---|
2-year | 5-year | |||
CTSB expression | 0.001 | |||
Positive | 90 | 42.5 % | 19.3 % | |
Negative | 78 | 62.8 % | 43.4 % | |
Gender | 0.518 | |||
Male | 110 | 57.9 % | 33.4 % | |
Female | 58 | 60.3 % | 39.6 % | |
Age (years) | 0.053 | |||
<50 | 123 | 61.2 % | 40.9 % | |
≥50 | 45 | 54.1 % | 35.4 % | |
Tumor size (cm)a | 0.001 | |||
<5 | 131 | 68.2 % | 47.6 % | |
≥5 | 37 | 49.8 % | 27.2 % | |
Serum HBsAg | 0.088 | |||
Positive | 147 | 54.3 % | 36.4 % | |
Negative | 21 | 62.3 % | 43.1 % | |
Serum AFP (ng/ml) | 0.001 | |||
<25 | 50 | 70.3 % | 51.3 % | |
≥25 | 118 | 52.6 % | 33.3 % | |
Cirrhosis | 0.031 | |||
Presence | 145 | 52.9 % | 23.3 % | |
Absence | 23 | 63.7 % | 43.6 % | |
UICC stage | 0.001 | |||
I + II | 100 | 75.2 % | 49.8 % | |
III + IV | 68 | 50.1 % | 24.5 % | |
Metastasis/Recurrence | 0.000 | |||
Yes | 133 | 43.4 % | 23.3 % | |
No | 35 | 67.2 % | 40.7 % | |
Edmondson grade | 0.005 | |||
Low (I/II) | 82 | 66.9 % | 42.8 % | |
High (III/IV) | 86 | 48.3 % | 27.1 % | |