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Table 1 mRNAs showing Fhit-dependent changes in ribosome loading

From: Impact of FHIT loss on the translation of cancer-associated mRNAs

Symbol Gene ID Log2 D1/E1
Coding region
 CDKN2C NM_001262 3.47
 IGSF9 NM_020789 3.42
 ATG16L2 NM_033388 3.39
 TP53I3 NM_004881 2.18
 MECP2 NM_004992 1.48
 CSRP2 NM_001321 1.31
 EEF2 NM_001961 −0.81
 GDA NM_001242505 −1.31
 IFIT1 NM_001548 −2.37
 LRRC73 NM_001012974 −4.39
5’-UTR
 ACSL1 NM_001995 3.69
 TROVE2 NM_004600 3.47
 ADAM9 NM_003816 1.51
 HIST1H2AD NM_021065 1.30
 H2AFZ NM_002106 0.72
 RACK1 NM_006098 −0.88
 RPL37A NM_000998 −2.01
  1. The Average Ribosome Density (ARD) for Ponasterone A-treated E1 and D1 cells was determined using RiboDiff and only those transcripts with an adjusted p value <0.05 were considered further. Column 3 shows the log2 induction ratio + Fhit(D1)/ -Fhit (E1). The upper panel lists mRNAs with changes in ribosomes bound to coding regions. The lower panel lists mRNAs with changes in ribosomes bound to the 5’-UTR using a cutoff of 25 nucleotides upstream of the annotated start codon