Fig. 4
From: Circular RNAs function as ceRNAs to regulate and control human cancer progression
circRNAs function as ceRNAs in regulating tumor invasion and migration. circRNAs regulate the invasion and migration of multiple factors in tumor cells, including RhoC, Notch, VEGFA, IL6R, and HNF-1β. These factors all participate in stimulating PI3K, which can activate AKT. This can promote angiogenesis and the epithelial-to-mesenchymal transition. circRNAs function as ceRNAs in this regulation