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Fig. 4 | Molecular Cancer

Fig. 4

From: Circular RNAs function as ceRNAs to regulate and control human cancer progression

Fig. 4

circRNAs function as ceRNAs in regulating tumor invasion and migration. circRNAs regulate the invasion and migration of multiple factors in tumor cells, including RhoC, Notch, VEGFA, IL6R, and HNF-1β. These factors all participate in stimulating PI3K, which can activate AKT. This can promote angiogenesis and the epithelial-to-mesenchymal transition. circRNAs function as ceRNAs in this regulation

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