Fig. 6

Characterization of Nptxr^−/− mice. a Genotyping of Nptxr^+/+, Nptxr^+/−, and Nptxr^−/− mice. b Direct sequencing of the 64-nucleotide deletion at the NPTXR locus of Nptxr^−/− mice. c Appearance of major organs from Nptxr^+/+, Nptxr^+/−, and Nptxr ^−/− mice. d Rotarod test of motor coordination and learning by Nptxr^+/+, Nptxr^+/−, and Nptxr ^−/− mice. e and f Renal e and liver f function tests of Nptxr^+/+, Nptxr^+/−, and Nptxr ^−/− mice