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Retraction Note to: Activation of LncRNA TINCR by H3K27 acetylation promotes Trastuzumab resistance and epithelial-mesenchymal transition by targeting MicroRNA-125b in breast Cancer
Molecular Cancer volume 21, Article number: 139 (2022)
The Original Article was published on 08 January 2019
Retraction note to: Mol Cancer 18, 3 (2019)
https://doi.org/10.1186/s12943-018-0931-9
The Editor-in-Chief has retracted this article. After publication, concerns were raised regarding image overlap between Figs. 1f and 3d, which the authors address by a Correction [1]. However, further concerns have been raised about potential image overlap with two other articles [2, 3]. Specifically, in Fig. 1g, one of the subpanels appears to be highly similar to an image in Fig. 5a in ([2], now retracted). In Fig. 3e, the top three images appear highly similar to the bottom three images (rotated) in Fig. 2f in [3].
The authors have provided the original data to address the concerns. However, the original data contains overlapping cell images and highly similar backgrounds in the western blot gel photographs. Additionally, the source, number and sex of animals are different between the Ethics approval document and the Methods section of the article.
The Editor-in-Chief therefore no longer has confidence in the presented data and the ethical standards of the study.
Huaying Dong has stated on behalf of all co-authors that they agree to this retraction.
References
Dong H, Hu J, Zou K et al. Correction to: Activation of LncRNA TINCR by H3K27 acetylation promotes Trastuzumab resistance and epithelial-mesenchymal transition by targeting MicroRNA-125b in breast Cancer. Mol Cancer. 2021;20:87. https://doi.org/10.1186/s12943-021-01385-9.
Qu A, Du L, Yang Y, Liu H, Li J, Wang L, et al. RETRACTED ARTICLE: Hypoxia-inducible MiR-210 is an independent prognostic factor and contributes to metastasis in colorectal cancer. PloS one. 2014;9(3):e90952. https://doi.org/10.1371/journal.pone.0090952.
Han M, Gu Y, Lu P, et al. Exosome-mediated lncRNA AFAP1-AS1 promotes trastuzumab resistance through binding with AUF1 and activating ERBB2 translation. Mol Cancer. 2020;19:26. https://doi.org/10.1186/s12943-020-1145-5.
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Dong, H., Hu, J., Zou, K. et al. Retraction Note to: Activation of LncRNA TINCR by H3K27 acetylation promotes Trastuzumab resistance and epithelial-mesenchymal transition by targeting MicroRNA-125b in breast Cancer. Mol Cancer 21, 139 (2022). https://doi.org/10.1186/s12943-022-01609-6
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DOI: https://doi.org/10.1186/s12943-022-01609-6