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Retraction Note to: Exosome-mediated lncRNA AFAP1-AS1 promotes trastuzumab resistance through binding with AUF1 and activating ERBB2 translation
Molecular Cancer volume 21, Article number: 143 (2022)
The Original Article was published on 05 February 2020
Retraction note to: Mol Cancer 19, 26 (2020)
https://doi.org/10.1186/s12943-020-1145-5
The Editor-in-Chief has retracted this article. After publication, concerns were raised regarding suspected image overlap with three other articles [1,2,3]. Specifically, in Fig. 2d, all subpanels appear to be highly similar to the images in Fig. 3c (rotated) in [1]. In Fig. 2f, a number of images appear highly similar to those in Figs. 5a and c in ([2], now retracted) and 3e in [3]. In addition, Fig. 5e appears to be drawn by hand.
The authors have provided the original data and revised figures to address the concerns. However, the original data contains highly similar backgrounds in the western blot gel photographs. Additionally, the source, number and sex of animals are different between the Ethics approval document and the Methods section of the article.
The Editor-in-Chief therefore no longer has confidence in the presented data and the ethical standards of the study.
Hui Cao agrees to this retraction. Mingli Han and Huaying Dong have stated on behalf of all co-authors that they agree to this retraction.
References
Zhang E, He X, Zhang C, et al. A novel long noncoding RNA HOXC-AS3 mediates tumorigenesis of gastric cancer by binding to YBX1. Genome Biol. 2018;19:154. https://doi.org/10.1186/s13059-018-1523-0.
Qu A, Du L, Yang Y, Liu H, Li J, Wang L, et al. RETRACTED ARTICLE: Hypoxia-inducible MiR-210 is an independent prognostic factor and contributes to metastasis in colorectal cancer. PloS one. 2014;9(3):e90952. https://doi.org/10.1371/journal.pone.0090952.
Dong H, Hu J, Zou K, et al. Activation of LncRNA TINCR by H3K27 acetylation promotes Trastuzumab resistance and epithelial-mesenchymal transition by targeting MicroRNA-125b in breast Cancer. Mol Cancer. 2019;18:3. https://doi.org/10.1186/s12943-018-0931-9.
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Han, M., Gu, Y., Lu, P. et al. Retraction Note to: Exosome-mediated lncRNA AFAP1-AS1 promotes trastuzumab resistance through binding with AUF1 and activating ERBB2 translation. Mol Cancer 21, 143 (2022). https://doi.org/10.1186/s12943-022-01610-z
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DOI: https://doi.org/10.1186/s12943-022-01610-z