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Correction: CircNTNG1 inhibits renal cell carcinoma progression via HOXA5-mediated epigenetic silencing of Slug

Molecular Cancer volume 22, Article number: 14 (2023) Cite this article

The Original Article was published on 19 December 2022

Correction: Mol Cancer 21, 224 (2022)

https://doi.org/10.1186/s12943-022-01694-7

Following the publication of the original article [1], the authors reported that the Additional file 5 is outdated. During the proof process, a mistake due to figure compilation was noticed in Additional file 5 Fig. S5J. The updated version has been provided in this erratum article, please see Additional file section. The authors would like to apologize for this negligence. It does not affect any of the interpretations or conclusions of the article.

Reference

  1. Liang Y, Cen J, Huang Y, et al. CircNTNG1 inhibits renal cell carcinoma progression via HOXA5-mediated epigenetic silencing of Slug. Mol Cancer. 2022;21:224. https://doi.org/10.1186/s12943-022-01694-7.

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Author notes

  1. Yanping Liang, Junjie Cen, Yong Huang, Yong Fang and Yunfei Wang contributed equally to this work.

Authors and Affiliations

  1. Department of Laboratory Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China

    Yanping Liang & Min Liu

  2. Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China

    Junjie Cen, Yong Fang, Guannan Shu, Yihui Pan & Junhang Luo

  3. Department of Emergency, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China

    Yong Huang

  4. Department of Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China

    Yunfei Wang, Jiaqi Dong, Mi Zhou, Yi Xu & Jiaxing Zhang

  5. Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China

    Kangbo Huang

  6. Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China

    Junhang Luo

Authors
  1. Yanping Liang
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  2. Junjie Cen
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  3. Yong Huang
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  5. Yunfei Wang
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  7. Yihui Pan
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  8. Kangbo Huang
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  10. Mi Zhou
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  11. Yi Xu
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  12. Junhang Luo
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  13. Min Liu
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  14. Jiaxing Zhang
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Corresponding authors

Correspondence to Junhang Luo, Min Liu or Jiaxing Zhang.

Supplementary Information

Additional file 5: Fig. S5.

The regulation of RCC by circNTNG1/miR-19b-3p/HOXA5 axis. A. Correlation analysis of circNTNG1 and miR-19b-3p in our own patient cohort (102 patients). B. Correlation analysis of miR-19b-3p and HOXA5 in our own patient cohort (102 patients). C. Correlation analysis of HOXA5 and Slug in our own patient cohort (102 patients). D. Immunoblotting of HOXA5, Slug and EMT markers with treatment of miR-19b-3p mimics or miR-19b-3p inhibitor in 769P cells. GAPDH was used as internal control. E. Immunoblotting of HOXA5, Slug and EMT markers with treatment of miR-19b-3p mimics or miR-19b-3p inhibitor in Caki-1 cells. GAPDH was used as positive control. F. Immunoblotting of HOXA5 and Slug in 786-O cells circNTNG1 overexpression salvage experiment. Cells were treated with circNTNG1 overexpression with/without miR-19b-3p mimics, and further salvaged with HOXA5 overexpression. GAPDH was used as positive control. G. Representative images (left) and quantification (right) data of Transwell migration/invasion assay of 786-O cells circNTNG1 overexpression salvage experiment. H. Representative images (left) and in vivo luciferase activity quantification (right) data of mouse tail-vein lung metastasis model. 786-O cells with vector, circNTNG1-overexpression, circNTNG1-overexpression+miR-19b-3p overexpression or circNTNG1-overexpression+miR-19b-3p overexpression+HOXA5 overexpression were used in the injection. Images were taken 8 weeks after the injection. I. Representative HE-stain images (left) and lung-metastasis foci quantification (right) data of 786-O mouse tail-vein lung metastasis model. J. Representative IHC images of HOXA5 in lung-metastasis foci from 786-O mouse tail-vein lung metastasis model. Data are mean ± SD, n = 3.

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Liang, Y., Cen, J., Huang, Y. et al. Correction: CircNTNG1 inhibits renal cell carcinoma progression via HOXA5-mediated epigenetic silencing of Slug. Mol Cancer 22, 14 (2023). https://doi.org/10.1186/s12943-023-01726-w

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  • DOI: https://doi.org/10.1186/s12943-023-01726-w

Molecular Cancer

ISSN: 1476-4598