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  • Erratum
  • Open Access

Erratum to: Bone-stromal cells up-regulate tumourigenic markers in a tumour-stromal 3D model of prostate cancer

Molecular Cancer201413:188

https://doi.org/10.1186/1476-4598-13-188

  • Received: 24 July 2014
  • Accepted: 24 July 2014
  • Published:

The original article was published in Molecular Cancer 2013 12:112

Correction

After the publication of this work [1] the authors’ informed the journal editors that Figure two (Figure 1 here) (B) is mislabelled and is a replica of Figure three(D). The correct version of Figure two(B) (Figure 1 here) is given below.
Figure 1
Figure 1

Integrins mediate morphology and invasive qualities of monocultured and co-cultured cells. (A-A”) PC3 cells grown in the presence or absence of either α6, β1 or both inhibiting antibodies. (A”) F-actin staining of PC3 cells in 3D culture. (B-B”) HS5 cells grown in the presence or absence of either α6, β1 or both inhibiting antibodies. (B”) F-actin staining of HS5 cells grown in the presence of both α6 and β1 inhibiting antibodies with acini formation (filled arrowhead). (C-C”) Co-cultured cells grown in the presence or absence of either α6, β1 or both inhibiting antibodies. (C”) In the presence of both α6 and β1 inhibiting antibodies, HS5 cells (STRO-1; green fluorescence) localised to the outer edge (filled arrowhead), while the PC3 cells (Cell Mask blue positive; STRO-1 negative) resided in the centre of the spheroid mass (unfilled arrowhead). (D) Quantification of the number of proliferating cells in PC3, HS5 and co-cultured cells over a 9 day period. (E) Quantification of the percentage of HS5 and PC3 cells proliferating in co-culture over a 9 day period. (F-F’) EDU labelling (red fluorescence) of HS5 (STRO-1 positive; green fluorescence) and PC3 cells (CellMask blue positive; STRO-1 negative) in co-culture at day 9. (G) Quantification of the number of cells to invade in the presence and absence of integrin inhibitors for PC3, HS5 and co-cultured cells. (H). Quantification of the percentage of invaded HS5 and PC3 cells in co-culture. (**p < 0.01, ***p < 0.001). Error bars denote S.E.M. Scale bars = 40 μm.

We regret any inconvenience that this inaccuracy may have caused.

Notes

Declarations

Authors’ Affiliations

(1)
Discovery Biology, Eskitis Institute for Drug Discovery, Griffith University, Nathan, 4111 Brisbane, QLD, Canada

References

  1. Windus LC, Glover TT, Avery VM: Bone-stromal cells up-regulate tumourigenic markers in a tumour-stromal 3D model of prostate cancer. Mol Cancer. 2013, 12: 112- 10.1186/1476-4598-12-112PubMed CentralView ArticlePubMedGoogle Scholar

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