Skip to main content

Erratum to: Bone-stromal cells up-regulate tumourigenic markers in a tumour-stromal 3D model of prostate cancer

The Original Article was published on 30 September 2013

Correction

After the publication of this work [1] the authors’ informed the journal editors that Figure two (Figure 1 here) (B) is mislabelled and is a replica of Figure three(D). The correct version of Figure two(B) (Figure 1 here) is given below.

Figure 1
figure 1

Integrins mediate morphology and invasive qualities of monocultured and co-cultured cells. (A-A”) PC3 cells grown in the presence or absence of either α6, β1 or both inhibiting antibodies. (A”) F-actin staining of PC3 cells in 3D culture. (B-B”) HS5 cells grown in the presence or absence of either α6, β1 or both inhibiting antibodies. (B”) F-actin staining of HS5 cells grown in the presence of both α6 and β1 inhibiting antibodies with acini formation (filled arrowhead). (C-C”) Co-cultured cells grown in the presence or absence of either α6, β1 or both inhibiting antibodies. (C”) In the presence of both α6 and β1 inhibiting antibodies, HS5 cells (STRO-1; green fluorescence) localised to the outer edge (filled arrowhead), while the PC3 cells (Cell Mask blue positive; STRO-1 negative) resided in the centre of the spheroid mass (unfilled arrowhead). (D) Quantification of the number of proliferating cells in PC3, HS5 and co-cultured cells over a 9 day period. (E) Quantification of the percentage of HS5 and PC3 cells proliferating in co-culture over a 9 day period. (F-F’) EDU labelling (red fluorescence) of HS5 (STRO-1 positive; green fluorescence) and PC3 cells (CellMask blue positive; STRO-1 negative) in co-culture at day 9. (G) Quantification of the number of cells to invade in the presence and absence of integrin inhibitors for PC3, HS5 and co-cultured cells. (H). Quantification of the percentage of invaded HS5 and PC3 cells in co-culture. (**p < 0.01, ***p < 0.001). Error bars denote S.E.M. Scale bars = 40 μm.

We regret any inconvenience that this inaccuracy may have caused.

References

  1. Windus LC, Glover TT, Avery VM: Bone-stromal cells up-regulate tumourigenic markers in a tumour-stromal 3D model of prostate cancer. Mol Cancer. 2013, 12: 112- 10.1186/1476-4598-12-112

    PubMed Central  Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Vicky M Avery.

Additional information

The online version of the original article can be found at 10.1186/1476-4598-12-112

Authors’ original submitted files for images

Below are the links to the authors’ original submitted files for images.

Authors’ original file for figure 1

Rights and permissions

Open Access  This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.

The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.

To view a copy of this licence, visit https://creativecommons.org/licenses/by/4.0/.

The Creative Commons Public Domain Dedication waiver (https://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Windus, L.C., Glover, T.T. & Avery, V.M. Erratum to: Bone-stromal cells up-regulate tumourigenic markers in a tumour-stromal 3D model of prostate cancer. Mol Cancer 13, 188 (2014). https://doi.org/10.1186/1476-4598-13-188

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1186/1476-4598-13-188